Dr. Polly Matzinger is running a lecture series on the “Danger model”, which is a great introduction to the concept, for new students of Immunology.
Polly originally proposed the “Danger Model” in 1992 to explain how Immune responses are initiated (Annu Rev Immunol. 1994;12:991-1045 ). The model has influenced work in both innate and adaptive immunity since then – and led to the discovery of endogenous molecules (DAMPs) that activate the immune system. She is now offering a series of lectures (available from the NIH videocast archive) which discuss different aspects of Immunology, from the vantage of the danger model. Polly is a great communicator – and beginner (as well as well-informed) immunologists will benefit from listening to the series. The links to individual lectures of the 7-part series are below (or found via the NIH site):